Major Employers in Upstate SC
Companies across Greenville, Spartanburg, Anderson & the Upstate region
Upstate South Carolina is home to some of the most influential companies across the globe. From global corporations to groundbreaking startups, the Upstate is a thriving, innovative business environment that attracts talent and investment from across the globe.
Whether you’re interested in success stories of companies in Greenville, SC, searching for insights about Spartanburg companies, or simply curious about the largest employers driving economic growth in the region, this list can help you find the information you need.
Largest Employers
Many of the biggest companies in Greenville and the Upstate region are well-known leaders in automotive and mobility, energy production, and engineered materials. The list below represents the region’s largest employers across industries with more than 2,500 employees.
Largest Employers – All Sectors ($2,500+ employees)
| Company Name | Employee Range | Line of Business |
| BMW Manufacturing Corp. | 5000+ | Automobile manufacturer |
| Clemson University | 5000+ | Public research university |
| Greenville County Schools | 5000+ | K-12 public education |
| Michelin, NA | 5000+ | Designs, manufactures, and sells tires for every type of vehicle |
| Prisma Health System | 5000+ | Healthcare system |
| Spartanburg Regional Healthcare System (SRHS) | 5000+ | Not for profit healthcare system, headquarters location |
| State of South Carolina | 5000+ | State government |
| United States Government | 5000+ | Federal government |
| Walmart | 5000+ | Retail stores; distribution centers |
| AnMed Health System | 2501 to 5000 | Hospital system |
| Bon Secours St. Francis Health System | 2501 to 5000 | General medical and surgical hospitals |
| GE Vernova | 2501 to 5000 | Gas turbines for energy use |
| HealthPRO Heritage | 2501 to 5000 | Therapy management services |
| Ingles Markets | 2501 to 5000 | Grocery stores |
| Milliken & Company | 2501 to 5000 | Manufactures textiles, fibers, and chemicals |
| Self Regional Healthcare | 2501 to 5000 | Short term acute care hospital |
| ZF | 2501 to 5000 | Automatic transmissions and axle system assemblies |
Major Manufacturing Companies
Upstate South Carolina is a manufacturing powerhouse, home to some of the most prominent manufacturers in the world.
From advanced automotive production to food & beverage manufacturing, manufacturing companies in Upstate SC benefit from the vast amount of skilled engineering and technical talent available across the region. This list below highlights the largest manufacturing companies in the Upstate region, with a focus on those employing 500 or more:
Largest Employers – Manufacturing (500+ employees)
| Company Name | Employee Range | Line of Business | County |
| BMW Manufacturing Corp. | 5000+ | Automobile manufacturer | Greenville, Spartanburg |
| Michelin, NA | 5000+ | Designs, manufactures, and sells tires for every type of vehicle | Anderson, Greenville, Laurens, Spartanburg |
| GE Vernova | 2501 to 5000 | Gas turbines for energy use | Greenville, Laurens |
| Milliken & Company | 2501 to 5000 | Manufactures textiles, fibers, and chemicals | Anderson, Cherokee, Greenville, Laurens, Spartanburg, Union |
| ZF | 2501 to 5000 | Automatic transmissions and axle system assemblies | Laurens, Spartanburg |
| AFL | 1001 to 2500 | Fiber optic products | Spartanburg |
| Arthrex South Carolina | 1001 to 2500 | Orthopedic medical device company | Anderson |
| BorgWarner Inc. | 1001 to 2500 | Powertrain components and transfer cases; EV battery systems | Oconee |
| DAA Draexlmaier Automotive of America LLC | 1001 to 2500 | Motor vehicle parts and accessories | Spartanburg |
| Eaton Corp. | 1001 to 2500 | Medium voltage assembly site | Greenwood, Spartanburg, Union |
| Electrolux Home Products | 1001 to 2500 | Top-freezer refrigerators and under-the counter refrigerators | Anderson |
| Freightliner Custom Chassis Corp. (FCCC) | 1001 to 2500 | Manufactures chassis for RV, walk-in van, commercial and school bus industries | Cherokee |
| International Vitamin Corporation (IVC) | 1001 to 2500 | Manufacturers viatmin preparations | Anderson, Greenville |
| Lockheed Martin Aeronautics | 1001 to 2500 | Aircraft MRO, Final Checkout & Assembly (FACO) of T-50A and F-16 | Greenville |
| Magna International | 1001 to 2500 | Products for the Automotive Industry | Greenville, Spartanburg |
| Nestle Prepared Foods Division | 1001 to 2500 | Frozen food specialties | Cherokee |
| OPMobility | 1001 to 2500 | Automotive interior systems, modules, and advanced technologies | Anderson, Spartanburg |
| Robert Bosch, LLC | 1001 to 2500 | Manufactures gasoline systems and electronic automotive components | Anderson |
| Sealed Air Corp. | 1001 to 2500 | Plastic film for food packaging | Greenville, Spartanburg |
| Techtronic Industries (TTI) | 1001 to 2500 | Power-driven hand tools | Anderson, Spartanburg |
| 3M Company | 501 to 1000 | Polyester film / Tape manufacturing | Greenville |
| BASF | 501 to 1000 | Produces specialty chemical catalysts, salts & solutions | Greenville, Oconee, Pickens, Spartanburg |
| Benteler Automotive | 501 to 1000 | Chassis components, front & rear axles | Spartanburg |
| Bosch Rexroth Corp. | 501 to 1000 | Hydraulic pumps for oil/gas, construction and agriculture industries | Greenville |
| Current HLI Solutions, Inc. | 501 to 1000 | Lighting manufacturers | Greenville |
| Dodge Industrial | 501 to 1000 | Manufactures enclosed gearing | Anderson, Greenville |
| First Quality Enterprises, Inc. | 501 to 1000 | Manufactures paper and tissue products | Anderson |
| First Solar Inc | 501 to 1000 | Photovoltaic (PV) solar and manufacturing company | Cherokee |
| Flexon Industries | 501 to 1000 | Watering hoses and extension cords | Anderson |
| Fuyao Glass America, Inc. | 501 to 1000 | Automotive and industrial glass processing | Greenville |
| Gestamp | 501 to 1000 | Automotive metal stampings and welded assemblies | Union |
| Glen Raven Custom Fabric, LLC | 501 to 1000 | Produces performance fabrics for solar protection | Anderson |
| House of Raeford Farms, Inc. | 501 to 1000 | Poultry & turkey processing | Greenville |
| Inman Mills | 501 to 1000 | Textile mills | Spartanburg |
| Isuzu North America Corporation | 501 to 1000 | Truck assembly | Greenville |
| Itron | 501 to 1000 | Electronic measuring devices | Oconee |
| JTKET | 501 to 1000 | Driveline and steering components | Greenville, Oconee |
| KYOCERA AVX Components Corporation | 501 to 1000 | Passive electronic components | Greenville |
| LifeMade Products, LLC | 501 to 1000 | Manufactures temperature-control packaging and single-use cutlery | Greenville |
| Lonza Capsules & Health Ingredients | 501 to 1000 | Hard capsule manufacturing | Greenwood |
| Pierburg US, LLC aka Rheinmetall Automotive | 501 to 1000 | Manufactures Permaglide & metallic bushings, thrust plates | Greenville |
| Reliable Automatic Sprinkler Company, Inc. | 501 to 1000 | Fire sprinklers and systems components | Pickens |
| SAGE Automotive Interiors | 501 to 1000 | Automotive fabrics and cloth | Abbeville, Greenville, Spartanburg |
| Siemens | 501 to 1000 | Products for electrical distribution and control | Greenville, Spartanburg |
| Sterilite Corp. | 501 to 1000 | Plastic houseware products | Laurens, Spartanburg |
| The Timken Company | 501 to 1000 | Manufactures tapered roller bearing systems | Anderson, Spartanburg, Union |
| VELUX Greenwood, LLC | 501 to 1000 | Designs and manufactures skylights | Greenwood |
| Vertiv + E&I Engineering USA Corp | 501 to 1000 | Electrical switchgear & power distribution solutions | Anderson |
| Yanfeng Automotive Interiors | 501 to 1000 | Automobile interior components | Laurens |
Source: Upstate SC Alliance Research, compiled 02/09/2026
Company Headquarters
Upstate South Carolina serves as the headquarters for a variety of global leaders across multiple industries. The list below highlights the largest headquarters in Greenville, Spartanburg and across the Upstate region, focusing on those key corporate offices with more than 500 employees:
Largest Headquarters
| Company | Employee Range | Type of Headquarters |
| BMW Manufacturing Corp | 5000+ | North American |
| Michelin North America, Inc | 5000+ | North American |
| GE Power | 2501 to 5000 | Divisional |
| Milliken & Company | 2501 – 5000 | Divisional |
| TD Bank | 1001 to 2500 | Regional |
| Fluor Corp. | 1001 to 2500 | Regional |
| DAA Draexlmaier Automotive of America LLC | 1001 to 2500 | North American |
| Techtronic Industries Power Equipment (TTI) | 1001 to 2500 | Divisional |
| AFL | 1001 to 2500 | North American |
| Freightliner Custom Chassis Corp. (FCCC) | 1001 to 2500 | North American; Divisional |
| SYNNEX Corp. – Greenville | 1001 to 2500 | National; Divisional |
| American Services, Inc. | 1001 to 2500 | National |
| Verizon Wireless | 1001 to 2500 | Regional |
| Lockheed Martin Aeronautics | 501 to 1000 | Divisional |
| Hamrick Mills | 501 to 1000 | National |
| Fujifilm Manufacturing USA, Inc | 501 to 1000 | Divisional |
| Nutra Manufacturing, an IVC Company | 501 to 1000 | Divisional |
| AVX Corp | 501 to 1000 | International |
| Hubbell Lighting, Inc. | 501 to 1000 | Divisional |
| Mitsubishi Polyester Film, Inc | 501 to 1000 | North American |
| Carolina Pride Foods, Inc | 501 to 1000 | National |
| Inman Mills | 501 to 1000 | National |
| Global Lending Services | 501 to 1000 | National |
| Tindall Corp. | 501 to 1000 | National |
| Precision Valve North America, Inc | 501 to 1000 | International |
| Sage Automotive Interiors | 501 to 1000 | International |
| American Credit Acceptance LLC | 501 to 1000 | National |
| GreenWood, Inc. | 501 to 1000 | National |
| World Acceptance Corp | 501 to 1000 | National |
Source: Upstate SC Alliance Research, compiled 2023
Interested in expanding your business to Upstate South Carolina? Learn how our team can help.
Elizabeth Watson, Director of Research & Strategic Initiatives
Upstate South Carolina serves as the headquarters for a variety of global leaders across multiple industries. The list below highlights the largest headquarters in Greenville, Spartanburg and across the Upstate region, focusing on those key corporate offices with more than 500 employees:
Elizabeth Watson serves as Director of Research & Strategic Initiatives for the Upstate SC Alliance. She is responsible for directing and executing the research efforts for the Upstate SC Alliance team and positioning the organization as the go-to resource for information, which includes compiling data and reports for prospects and investors, as well as working with industry partners to provide the most up to date information about the Upstate. Watson is also an integral part of the Upstate’s participation with the Global Cities Exchange, a joint partnership of the Brookings Institution and JPMorgan Chase. Watson joined the Upstate SC Alliance in 2011 after 11 years with GSA Business Report.
Watson graduated from the Honors College at the College of Charleston with a BA in English, a BA in French and a minor in Arts Administration.